Fifth-grader Eric's life transforms when he encounters a unicorn in the woods around Chinaberry Creek and discovers a special veterinary clinic that cares for "supernatural exotic patients."

While helping to set up a Santaland outside Walton Cottage Hospital, Mandy and James spot a stray Jack Russell terrier. They also befriend Charlie, a young patient, who desperately wants a dog for Christmas. Can they bring the two together?

When Papillon's hiccups cause him to stop floating, Miss Tilly rushes him to a clinic where, once he feels better, he makes new friends.